Two pathways for prostaglandin F2α synthesis by the primate periovulatory follicle
نویسندگان
چکیده
منابع مشابه
Microsomal prostaglandin E synthase-1 (mPGES-1) is the primary form of PGES expressed by the primate periovulatory follicle.
BACKGROUND Prostaglandin E2 (PGE2) has been identified as the key ovulatory PG in the primate follicle. Follicular PGE2 levels increase just before the expected time of ovulation, suggesting that the midcycle LH surge induces the expression of enzymes involved in PGE2 synthesis. METHODS To identify the specific form(s) of prostaglandin E synthase (PGES) expressed by the primate periovulatory ...
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Recent progress in prostaglandin F2α ethanolamide (prostamide F2α) research and therapeutics.
Prostamide (prostaglandin ethanolamide) research emerged from two distinct lines of research: 1) the unique pharmacology of the antiglaucoma drug bimatoprost and 2) the discovery that endocannabinoid anandamide was converted by COX-2 to a series of electrochemically neutral prostaglandin (PG) ethanolamides. Bimatoprost pharmacology was found to be virtually identical to that of prostamide F2α. ...
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2008
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-07-0514